Health Effects of Air Conditioning

To get clean, fresh air from your unit, you do require to undertake regular AC duct cleaning.

Importance of AC unit

A few decades ago, it was only the rich & the celebrity who could invest & install in this appliance. However, in today’s modern era, where technology rules, it has become possible for every household to own one. They can be found installed in homes, offices, and even in several public transport systems. Unfortunately, faulty maintenance & viciously low temperatures cause severe health complications. People have reported facing common disorders and significant ailments.

Advantages of AC unit on your health

Since Dubai is a place that experiences extreme heat, studies have shown that there is a negative impact on an individual’s physical activities and intelligence. This can be rectified by installing the AC unit and enjoying the cold air. But you need to hire AC duct cleaning companies like Kimiclean to keep the unit in good running condition.

Improves job performance, see AC Maintenance Career in Dubai
Enhances comfort level
Proper installation and regular maintenance of the unit, improves and renews air quality
HVAC system helps to eliminate harmful external allergens such as pollen.
A lower temperature reduces sweating, thereby decreasing the risks of dehydration.
Chilled/lower temperatures reduce the existence of insects & parasites.
Improved physical & intellectual activity.
Disadvantages of the AC unit on your health
Running the unit 24/7 does result in several health-related issues.
Ambient noise causes noise pollution.
Regular usage dries mucous membrane & skin.
Unexpected changes experienced in temperature & humidity affects the respiratory system sharply.
It can cause eye conditions such as alos, blepharitis, and conjunctivitis.
Associated with throat irritation, hoarseness, pharyngitis, and chronic rhinitis.
Fungi & airborne dust causes allergic reactions.
Air circulation may transmit harmful infectious respiratory diseases.
If allergens are present indoor, then you can suffer from headaches, nasal issues, dizziness, difficulty in breathing, and itchy eyes. Asthma attacks and pneumonia may develop in extreme cases.
Running the system continuously may only worsen allergic symptoms if the unit is not properly maintained and cleaned. But with regular AC duct cleaning, the problem can be solved.
Spending long hours will only make you heat intolerant, especially when you go out in the heat.
Points to follow to stay protected against the above disadvantages
Go sincerely through manufacturer instruction and find out about replacing/cleaning the air filters.
Allow fresh air within the room by opening up all windows and remove pollutants.
After every ten years, replace the existing unit with a new one.
Choose only certified & experienced AC duct cleaning technicians to carry out annual maintenance checks.
Replace cabin filters of your car after completing every 12,000 – 15,000 miles.
Use fan-only mode mostly on the unit.
Following the above can help you to enjoy your AC unit throughout the year.

Domestic and International Tax Consultants: The Difference

If you have financial dealings that involve other countries or currencies, such as foreign property, assets, or investments, odds are you are not handling all of your finances on your own. You have probably recognized that such complex financial dealings require the guidance of an accountant, especially come tax season, to ensure that you are falling within the tax laws of your own country and those within which you have investments. You may be wondering if a standard accountant is sufficient to help you, or if you should seek the services of a specialized international tax consultant. You may also be wondering if there is a significant difference in the services provided by each.You can be assured that there are some differences in expertise and qualifications. Here are the benefits of hiring an international tax consultant.EducationQuite often, an international tax consultant will have some type of education that qualifies them to specialize in international taxes over and above standard accounting qualifications. They may have majored in international business or accounting while completing their bachelor’s degree, or they may have completed a post-degree certification in international tax consulting. This provides them with a better knowledge of the intricacies of international taxes.Of course, education is more than classrooms and certifications. A qualified international tax consultant keeps him or herself educated and up to date on changes in international tax law and best practices. Though a domestic accountant may stay somewhat up to date on those matters, they likely approach it with less dedication.ExperienceIt’s not just formal education that differentiates an international tax consultant from a standard accountant; it’s also experience. Unless you’re hiring a rookie accountant, your international tax consultant will have been in the business for some time, and he or she will be familiar with the ins and outs of international tax law. Odds are he or she will have already encountered any complex or challenging situation you may find yourself in, and he or she will be able to handle it with more certainty and finesse than a standard accountant who has less experience in international tax.FlexibilityOne of the best parts about hiring international tax consultants is that they are still accountants. They still have the same base level of training and experience as any other accountant; they just happen to also have an extra layer of expertise on top of that. That means they are also qualified to handle your domestic accounting, taxes, and financial matters. In other words, they should be able to handle your entire portfolio. This saves you from having to turn to multiple accountants or financial consultants, which only increases the risk of error and creates a hassle for you. An international tax consultant can handle your finances in a comprehensive, thorough manner.Though a standard, domestic accountant has a great deal of value and can provide great services, when it comes to international taxes, investments, and assets, your best bet is always to seek out the specialized services of an international tax consultant.

Know How To Predict Drug-Drug Interactions Of Your Test Compound Using CYP Induction Assay

Cytochrome P450 proteins are significant drug metabolizing enzymes. For pharmaceutical companies developing new compounds, the evaluation of CYP induction is a critical step in assessing drug safety in regards to transporter interaction. CYP induction helps reduce drug liability by identifying potential drug-drug interactions that may cause unwanted adverse effects.Why to Choose CYP Induction Assay?Cytochrome P450 enzymes are vital for the metabolism of numerous medications. There are approximately 60 enzymes present in this class, six of them metabolize 90 percent of drugs, with the most important enzyme being CYP3A4.Genetic variations in these enzymes may affect an individual’s response to generally recommended drug classes, including beta blockers and antidepressants.Cytochrome P450 enzymes can be induced by drugs, resulting in clinically significant drug-drug interactions that can cause unwanted adverse reactions or therapeutic failures. Therefore, it is vital to assess the CYP induction potential of a test compound.The Cytochrome P450 (CYP) Induction Assay from IONTOX is designed to meet the needs of the client based on the criteria and recommendations of the FDA guidelines on Drug Interaction Studies.Exposure times for the CYP Induction Assay is usually 72 hours, followed by mRNA and CYP1A2, CYP2B6 and CYP3A4 gene expression level assessment.Key Points About Cytochrome P450 (CYP) Induction Assay• Enables measurement of CYP1A2, CYP2B6 and CYP3A4 at the protein level.• Delivers accurate, high quality data with the study based on the criteria and recommendations of the FDA guidelines.So, assess drug-drug interactions of your test compound using the CYP Induction Assay.For more information regarding the CYP Induction Assay, visit https://www.iontox.com/cyp-induction-assay/ today.